• Product Name: Sodium Acetylated Hyaluronate (AcHA)
  • Molecular Formula:(C14+2xH20+2xNO11+xNa) n, x is the degree of acetylation
  • Purity:≥99%
  • Molecular Weight:1,000-2,000,000Da(Customizable)
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Product Details

  • CasNo: 158254-23-0
  • Molecular Formula: (C14+2xH20+2xNO11+xNa) n, x is the degree of acetylation
  • Appearance: White or light yellow powder
  • Packing: 1kg/bag or according to customer's requirements
  • Purity: ≥99%
  • Cheapest! Quality Manufacturer Supply High quality Sodium Acetylated Hyaluronate (AcHA) Manufacturer in stock/Best price CAS NO.158254-23-0.

    Quality Factory Supply Top Purity 158254-23-0 white or light yellow powder In Stock with Fast Shipping

    • Molecular Formula:(C14+2xH20+2xNO11+xNa) n, x is the degree of acetylation 
    • Molecular Weight: 1000Da-2,000,000Da(Customizable)
    • Appearance/Colour:white or light yellow powder
    • Vapor Pressure:-

     Sodium Acetylated Hyaluronate (AcHA) (Cas 158254-23-0) Usage

    Chemical Properties

    white or light yellow powder, no special odor 


    Sodium Acetylated Hyaluronate is a derivative obtained by acetyl substitution on four hydroxyl groups of sodium hyaluronate disaccharide structure. Due to the introduction of a large number of acetyl groups, the lipophilicity of acetylated hyaluronate is greatly improved. Compared with traditional sodium hyaluronate, acetylated sodium hyaluronate is more efficient in moisturizing, repairing skin barrier and increasing skin elasticity, as well as better transdermal and hyaluronidase resistance.

    Sodium Acetylated Hyaluronate (AcHA), also known as Acetylated Hyaluronate Sodium, is a modified form of hyaluronic acid, a naturally occurring substance in the body that helps to hydrate and lubricate tissues. AcHA has several uses in the cosmetic and pharmaceutical industries, including as a moisturizing agent in skincare products and as a drug delivery system for certain medications. Its unique chemical structure allows it to penetrate the skin more deeply than regular hyaluronic acid, providing longer-lasting hydration and anti-aging benefits. In addition, AcHA has been shown to have anti-inflammatory and wound-healing properties, making it a potentially useful ingredient in topical treatments for skin conditions such as eczema and psoriasis. Overall, Sodium Acetylated Hyaluronate is a versatile compound with many potential applications in the fields of cosmetics and medicine.


    158254-23-0 Relevant articles

    The anti‐wrinkles properties of sodium acetylated hyaluronate

    Marie Meunier MS, Amandine Scandolera PhD, Emilie Chapuis BS, Laura Lapierre BS, Jérôme Sandré MD, Gerhard Brunner PhD, Martin Lovchik PhD, Romain Reynaud MS

    , Journal of Cosmetic Dermatology, Volume21, Issue7 July 2022 Pages 2749-2762

    Normal human dermal fibroblasts (NHDFs) obtained from a donor who had an abdominal surgery under informed consent were seeded at 250 000 cells per well in 6-well plates. After 72 h of culture, the cells were stimulated for 24 h with sodium acetylated hyaluronate or with non-acetylated hyaluronate, which are same molecular weight (15 kDa) as a control at 0.01% (w/v) for NHDF in free Dulbecco's Modified Eagle's Medium (DMEM from Gibco, Thermo Fisher Scientific).

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